The learning capacity would be temporarily reduced by the end of the premenopausal according to a study published in the journal Neurology. Gail Greendale, University of California at Los Angeles and his colleagues conducted the study with 2362 women aged 42-52 years who had at least one menstrual period during the three months preceding the study.
They passed the tests of verbal memory, working memory and speed of thinking (information processing speed) at different stages of the menopausal transition:

- The premenopausal (no change in the menstrual cycle);
- The beginning of the perimenopause (irregular cycles but not in the absence of the rule for a period of three months);
- Late perimenopause (no rule for 3-11 months);
- Postmenopause (no rule for 12 months).
The performance on these tests improved with repetition. But this improvement was less significant in the perimenopause. Improving the speed of thought in late perimenopause only 28% of that of premenopausal. The improvement in verbal memory in early and late perimenopause was only 29% and 7% of that of premenopausal. “Combined, these results indicate that early and late perimenopause, women do not learn as well as during other stages of transition,” says Greendale.
“These results are consistent with the memory problems reported by 60% of women like symptoms during the menopausal transition,” she said. “The good news is that these learning effects seem to be temporary. The results show that, postmenopause, learning comes at the premenopause. ”
The results also show that hormone replacement therapy, estrogen and progesterone before menopause improve verbal memory and speed of thought. But instead, those hormones after the last menstrual period, had a negative effect postmenopausal women who took hormones did not show improvement as opposed to those who did not. “Our results suggest that the critical period for the benefits of estrogen and progesterone on the brain can be pre-menopausal, but these results should be interpreted with caution,” said Greendale.

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